Mayo Clinic Center for Sleep Medicine

Transvenous Phrenic Nerve Stimulation for Central Sleep Apnea

What is transvenous phrenic nerve stimulation?  When should we use it for patients with central sleep apnea?  Dr. Timothy Morgenthaler, a sleep specialist at Mayo Clinic, answers these questions.

How should we manage patients with treatment emergent central sleep apnea?

Do all patients with CPAP related treatment emergent central sleep apnea need a change in management?  Dr. Timothy Morgenthaler, a sleep specialist at Mayo Clinic, answers this question.

CSA in Heart Failure: Current Controversies

Is CSA harmful in patients with heart failure? When should it be treated?  What is the role of augmented servo-ventilation? Dr. Sean Caples, a sleep specialist at Mayo Clinic, answers these questions.

Idiopathic Hypersomnia: Current Diagnosis and Treatment

Idiopathic hypersomnia is probably at least as common and possibly more common than narcolepsy.  In this podcast, Dr. Michael Silber discusses current approaches to its diagnosis and pharmacologic management.

The Discovery of REM Sleep

Many date the start of the field of Sleep Medicine to the discovery of REM sleep by Eugene Aserinsky and Nathaniel Kleitman in 1953.  But was it actually discovered 27 years earlier by Russian investigators?  In this podcast Dr. Michael Silber discusses the fascinating story of how REM sleep was identified and what this means for Sleep Medicine.

New hope for Narcolepsy: Is the Future Nearly Here?

The number of medications available to treat narcolepsy has grown dramatically in the last few years. While these have changed the landscape for patients, the future may hold even better treatments. In this podcast, Dr. Michael Silber discusses the currently available new medications and the development of orexin receptor agonists which may transform narcolepsy management.

The Diagnosis of Narcolepsy: Where does CSF orexin fit in?

How should we diagnose narcolepsy? In this podcast, Dr. Michael Silber explains when measuring CSF Orexin-A can be helpful and how to interpret the results.

45 Years of the MSLT: Where are we now?

The multiple sleep latency test was developed in 1978. While it is still the standard test used for the diagnosis of central disorders of hypersomnolence, its interpretation is complex and many factors can affect the validity of its results. In this podcast, Dr. Michael Silber discusses the practical use of the MSLT in 2024.